Prior to her appointment as Undersecretary of the Department of Trade and Industry, Usec. Blesila A. Lantayona was the Assistant Secretary of DTI-Regional Operations Group, in-charge of Kapatid Mentor ME, Shared Service facilities, Industry Cluster Enhancement Project, Great Women Project 2, among others.
She holds an MBA Degree in International Business from Ecole Europeenne des Affaires (European School of Management) in Paris, France.
Her career in the civil service started in NEDA Region XI then moved to DTI in various technical positions at first, then as Provincial Director of DTI-Davao del Sur, as Assistant Regional Director of DTI-Region XI and was later appointed as Regional Director of DTI-Region III (Central Luzon).
In September 2019, she was appointed as the Supervising Undersecretary of the DTI-Regional Operations Group in-charge of the 16 Regional Offices, 81 Provincial Offices and the Bureau of Small Micro Enterprise Development.